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Cleveland Clinic physician-scientist Stanley L. Hazen, M.D., Ph.D., has been elected to the prestigious National Academy of Medicine (formerly known as the Institute of Medicine).
NAM members are chosen by current active members. Candidates are selected based on major contributions to the advancement of the medical sciences, healthcare, and public health.
Dr. Hazen has made pioneering discoveries in the fields of atherosclerosis and inflammatory disease research that are impacting clinical practice. He made the seminal discovery linking specific gut microbe pathways and products to the development of cardiovascular and metabolic diseases, including atherosclerosis, thrombosis, heart failure and chronic kidney disease.
In a recent landmark study his research shows drugging microbial pathways can serve as a means for blocking diet-dependent atherosclerosis. His comprehensive work establishes a new understanding of diet/gut microbe/host interactions in diseases, and has spawned development of both new diagnostic tests and therapeutic approaches for the treatment and prevention of cardiovascular diseases and metabolic disorders.
Hazen’s numerous other discoveries include defining pathways white blood cells use to generate reactive oxidants, and their functional importance in heart disease. His work lays the foundation for diagnostic tests in clinical use for cardiovascular disease risk assessment worldwide.
“I am honored and humbled to receive this award,” said Dr. Hazen. “I also want to thank and credit both the members of my research group and my colleagues at the Cleveland Clinic Lerner Research Institute who have helped and supported me in making the discoveries and advances over the years.”
Both a practicing physician and researcher, Dr. Hazen holds many leadership roles at Cleveland Clinic. He is the section head for Preventive Cardiology & Rehabilitation in the Robert and Suzanne Tomsich Department of Cardiovascular Medicine in the Miller Heart & Vascular Institute, as well as chair of the Department of Cellular & Molecular Medicine in the Lerner Research Institute. He also holds the Jan Bleeksma Chair in Vascular Cell Biology and Atherosclerosis and the Leonard Krieger Chair in Preventive Cardiology.
Dr. Hazen has published over 350 peer-reviewed articles, invited reviews and book chapters and has received many honors and awards for his research, including election to the American Society for Clinical Investigation (ASCI) and the American Association of Physicians (AAP). He also is an elected fellow of the American Association for the Advancement of Science (AAAS). He also serves as reviewer for more than 20 scientific and clinical journals.
Dr. Hazen earned a bachelor’s degree and dual M.D./Ph.D. degree from Washington University School of Medicine in St. Louis, Missouri. He went on to complete an internal medicine residency and fellowship in endocrinology diabetes and metabolism at Barnes-Jewish Hospital, also in St. Louis.
Cleveland Clinic staff are well represented among the 19,000 members of the NAM. Among the many distinguished physicians and scientists elected to the Institute/Academy are: Irvine H. Page, M.D., a hypertension expert and first chair of the Division of Research, named in 1970, the year the IOM was established; George R. Stark, Ph.D., distinguished scientist and former chair of the Lerner Research Institute; and Cleveland Clinic President and CEO Toby Cosgrove, M.D. Also honored over the years have been Drs. Manuel D. Cerqueira, Charis Eng, C. Martin Harris, Joanne Hilden, William S. Kiser, Eric Kodish, Beth A. Overmoyer, Roger Macklis, Geoffrey Rosenthal, James S. Taylor, and James B. Young.
Cleveland Clinic is a nonprofit multispecialty academic medical center that integrates clinical and hospital care with research and education. Located in Cleveland, Ohio, it was founded in 1921 by four renowned physicians with a vision of providing outstanding patient care based upon the principles of cooperation, compassion and innovation. Cleveland Clinic has pioneered many medical breakthroughs, including coronary artery bypass surgery and the first face transplant in the United States. Cleveland Clinic is consistently recognized in the U.S. and throughout the world for its expertise and care. Among Cleveland Clinic’s 81,000 employees worldwide are more than 5,743 salaried physicians and researchers, and 20,160 registered nurses and advanced practice providers, representing 140 medical specialties and subspecialties. Cleveland Clinic is a 6,690-bed health system that includes a 173-acre main campus near downtown Cleveland, 23 hospitals, 276 outpatient facilities, including locations in northeast Ohio; Florida; Las Vegas, Nevada; Toronto, Canada; Abu Dhabi, UAE; and London, England. In 2023, there were 13.7 million outpatient encounters, 323,000 hospital admissions and observations, and 301,000 surgeries and procedures throughout Cleveland Clinic’s health system. Patients came for treatment from every state and 132 countries. Visit us at clevelandclinic.org. Follow us at twitter.com/CleClinicNews. News and resources available at newsroom.clevelandclinic.org.
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