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Medical illustration of atherosclerosis.

Cleveland Clinic First-In-Human Trial of CRISPR Gene-Editing Therapy Shown to Safely Lower Cholesterol and Triglycerides

One-time infusion of investigational CRISPR-Cas9 therapy found to safely reduce LDL cholesterol by 50% and triglycerides by about 55% in Phase 1 trial

Study Identifies Gene Variant That Increases Heart Failure Risk in People of African Ancestry

Discovery reveals new disease pathway tied to how the heart uses certain fuels to generate energy; Cleveland Clinic to lead next stage of translational research through new cardiovascular genomics initiative

New Cleveland Clinic Research Finds Up to 5% of Americans Carry Genetic Mutations Associated with Cancer Risk

Results highlight the importance of routine cancer screenings, suggest genetic testing should go beyond high-risk groups

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