Novel Imaging Biomarker to Help Predict Coronary Inflammation

MUNICH, Germany:  Researchers at Cleveland Clinic, University of Oxford and University of Erlangen have identified a novel imaging biomarker, which has been found to be able to predict all-cause and cardiac mortality by measuring inflammation of fatty tissue surrounding the coronary arteries. Coronary artery inflammation inhibits fatty tissue formation surrounding the blood vessels, known as … Read More

Potential New Class of Drugs Developed at Cleveland Clinic May Reduce Cardiovascular Risk by Targeting Gut Microbes

Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut. Unlike antibiotics, which non-specifically kill gut bacteria and can lead to adverse side effects and resistance, the new class of compounds prevents microbes from making a harmful molecule linked to … Read More

Cleveland Clinic Researcher Receives $2.8 Million Grant to Improve Heart Transplant Outcomes

The National Institutes of Health has awarded Cleveland Clinic researcher Eileen Hsich, M.D., $2.8 million over four years to evaluate disparities in survival among heart failure patients before and after heart transplantation and to create tools that would optimize outcomes. “We believe that to improve care for those with heart failure awaiting transplant, we must … Read More

Cleveland Clinic-Led Study Shows Leadless Pacemaker Patients Experience Less Complications

Patients receiving leadless pacemakers experience overall fewer short-term and mid-term complications than those receiving traditional transvenous pacemakers, a Cleveland Clinic-led research study found. The study was published today in the journal Heart Rhythm. Approximately one million pacemakers are implanted annually, providing electrical stimulation to regulate a patient’s heartbeat. Conventional pacemakers are surgically placed under the … Read More

Preventive Aortic Surgery Shows Positive Outcomes For Patients with Loeys-Dietz Syndrome

San Diego: Cleveland Clinic researchers found that patients with Loeys-Dietz Syndrome (LDS) had better outcomes when they were treated early with preventative aortic surgery. The research was presented at the American Association for Thoracic Surgery’s 98th Annual Scientific Session and simultaneously published in the Journal of Thoracic and Cardiovascular Surgery.  LDS is a recently recognized disease, identified in … Read More

Cleveland Clinic-Led Trial Reveals Differences in Pain-Relieving Drugs When Combined with Aspirin

A landmark 2016 Cleveland Clinic study of widely used pain-relieving drugs showed that celecoxib (Celebrex) was associated with comparable cardiovascular safety and better gastrointestinal (GI) and kidney safety when compared with either naproxen (Naprosyn) and ibuprofen (Motrin). A new substudy, published today in the Journal of the American College of Cardiology, analyzed outcomes in PRECISION … Read More

Cleveland Clinic’s Stanley Hazen, M.D., Ph.D., Recognized as 2017 Distinguished Scientist by The American Heart Association

Stanley Hazen, M.D., Ph.D., chair of the Department of Cellular & Molecular Medicine in the Lerner Research Institute and section head of Preventive Cardiology & Rehabilitation in the Miller Family Heart & Vascular Institute at Cleveland Clinic, has been named by the American Heart Association (AHA) a Distinguished Scientist for 2017. According to the AHA, the Distinguished Scientist … Read More

About 30 Percent of Retired NFL Players in Cleveland Clinic Study Have Enlarged Aortas

Cleveland Clinic researchers found that a group of retired National Football League (NFL) players have significantly larger aortas when compared to men in the general population. The clinical significance of these findings is unknown and will require further evaluation, researchers said, though enlarged aortas are a known risk factor for life-threatening aortic dissections or aortic … Read More