Cleveland Clinic Researchers Reveal Biomarker for Guiding Prostate Cancer Treatment

Back-to-back discoveries from Cleveland Clinic demonstrate for the first time how a testosterone-related genetic abnormality can help predict individual patient responses to specific prostate cancer therapies. The studies, published in the October 12 issue of JAMA Oncology, suggest that men who inherit this variant would benefit from a personalized treatment plan that targets specific hormonal … Read More

A Better Way to Measure Mortality Trends?

A new study from Cleveland Clinic suggests long-term mortality trends may be better understood by focusing on life-years lost — remaining life expectancy for a decedent — instead of solely looking at cause of death. The research published today in the American Journal of Public Health, calculated years of life lost to the top 15 … Read More

Bariatric Surgery or Medication/Lifestyle Modifications: Which has Better Long-term Effect on Type 2 Diabetes? Cleveland Clinic-Led Multicenter Trial to Assess Approaches

A team of Cleveland Clinic researchers is leading a first-of-its-kind multicenter clinical trial to assess the long-term outcomes of bariatric/metabolic surgery compared to medical and lifestyle therapy for treating Type 2 diabetes. The Alliance of Randomized Trials of Medicine versus Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D) consortium members are Cleveland Clinic, Joslin Diabetes Center/Brigham … Read More

Cleveland Clinic Researchers Discover Similarities Between Next-Generation Prostate Cancer Drugs

  Cleveland Clinic researchers have shown for the first time how a class of advanced prostate cancer drugs are processed in the body and how their anti-tumor activity might change depending on how they are metabolized. Their pre-clinical findings, just published in Cell Chemical Biology, may lay the foundation for improving therapies for treatment-resistant, aggressive … Read More

Cleveland Clinic Researcher Receives Top Ten Clinical Research Achievement Award

Cleveland Clinic physician-researcher Nima Sharifi, M.D. was recognized as a Top Ten Clinical Research Achievement awardee by the Clinical Research (CR) Forum, a national organization of senior researchers and thought leaders from the nation’s leading academic health centers. Dr. Sharifi was selected for his research published in the October 2016 edition of The Lancet Oncology, … Read More