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SearchIn 2025, we reimagined what it means to partner with Cleveland Clinic Innovations and expanded the ways we bring innovations to patients at scale. In doing so, we saw 58 new license agreements and 207 new invention disclosures. We announced a collaboration with Khosla Ventures, one of Silicon Valley’s leading investors in healthcare commercialization and technology—an example of how we’re strategically connecting outside innovation to our world-class ecosystem of research, discovery and clinical talent.
Innovation rarely happens in a straight line, and at Cleveland Clinic Innovations (CCI), our approach is ever evolving.
Our 2025 Year in Review highlights how far we’ve come in building systems and processes designed for the future of healthcare innovation. It showcases new, effective pathways we’ve created for partnering with us – accelerating the journey of new inventions to patients while reducing risk along the way.
Read our 2025 Year in Review
As we look toward opportunities in 2026, we’re proud to reflect on a year marked by momentum and measurable impact:
In 2025, we delivered:
We advanced deployment of clinically validated artificial intelligence in sepsis care, oncology, neurology and other critical specialties to improve patient outcomes at scale.
We forged new external partnerships, including one with Khosla Ventures, providing pipelines to emerging technologies in artificial intelligence, digital health and next-generation therapeutics.
Our world-class ecosystem of research, discovery and unmatched clinical talent elevates our credibility as a commercialization partner of choice. Today, our 37 portfolio companies are progressing through key regulatory milestones and advancing through funding rounds. 2025 showed what’s possible when clinical expertise, data and the right partnerships come together. Stay connected with us as we continue to transform healthcare through innovation and technological advancement. If you are exploring licensing, co-development, venture collaboration or strategic investment opportunities, our team is ready to help you discover what’s possible.
