May 20, 2022/News Releases

Cleveland Clinic Breaks Ground on Cole Eye Institute Expansion

Expansion includes construction of the Jeffrey and Patricia Cole Building at Cole Eye Institute

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Cleveland Clinic hosted a ceremonial groundbreaking today for the construction of the 150,000-square-foot Jeffrey and Patricia Cole Building at Cole Eye Institute, and renovation of the existing 130,000-square-foot Cole Eye Institute building constructed in 1999. The two buildings will be connected to create an integrated eye center designed to deliver an outstanding patient experience, as well as leading edge eye care, research and education.

Concept rendering of the Jeffrey and Patricia Cole Building at Cole Eye Institute.

Cole Eye Institute is among the world’s most advanced eye centers and a leader in ophthalmologic research. It is consistently ranked in the top 10 in the nation by U.S. News & World Report. Cole Eye serves more than 330,000 patients annually – among the highest volumes in the nation. The institute includes more than 140 staff physicians and researchers who diagnose, treat and investigate all conditions of the eye, including macular degeneration, cataracts, glaucoma and diabetic retinopathy.

“This project is rooted in our vision to make Cleveland Clinic the best place for care anywhere,” said Cleveland Clinic CEO and President Tom Mihaljevic, M.D. “Through expanded facilities, we can improve access and touch more lives, which we see as our ethical imperative. The world looks to us for innovative solutions and projects like this that position Cleveland Clinic to thrive in today’s complex healthcare environment.”

This expansion was made possible by a lead gift of $31.5 million from Jeffrey A. Cole and his wife Patricia O’Brien Cole. Mr. Cole and his company Cole National, which at one time was the world’s largest provider of commercial vision care services and based in Cleveland for 60 years, also contributed the lead gift that established the Cole Eye Institute in 1999.

“It has been a long journey since 1999 to today’s groundbreaking,” said Jeffrey Cole. “But it marks the opportunity for Cole Eye to further serve more patients in need of eye care and to become the number one program in the nation.”

Philanthropy has been critical to this expansion with $125M raised to support this project, including funds for capital expenses and expanding patient care, research and education.

Design plans for the $177 million renovation and four-story new structure, located on Euclid Avenue between E. 100th and E. 105th streets, are centered on a team-based operating model to improve access for patients, increase capabilities and enhance patient experience. The new facility will feature an ophthalmic surgical center that will include 12 operating rooms, three refractive surgery procedure rooms and 50 eye exam rooms.

“The expansion of Cole Eye Institute has been fueled by our exponential growth over the past decade,” said Daniel F. Martin, M.D., Chairman of Cole Eye Institute and the Barbara and A. Malachi Mixon III Institute Chair of Ophthalmology. “This new leading-edge facility will allow our caregivers to continue providing exceptional clinical care and to facilitate innovative breakthroughs in research.”

Renovation plans also include the expansion of the Louise Timken Ophthalmic Education Center, which will facilitate growth of eye research, an expanded education and training simulation center and centralization of multiple ophthalmology research labs. The space will also feature a new Center of Excellence in Ophthalmic Imaging.

The Cole Eye Institute leadership board, comprised of 14 community leaders, was instrumental in helping to move this project forward. Led by Carole Hoover and the late Mal Mixon, the group of advisors was very supportive of this work.

Designed by Bostwick Design Partnership and HGA, and constructed by Whiting-Turner Construction, the project is expected to begin in late summer with completion at the end of 2025. Patient care will continue during construction.

About Cleveland Clinic

Cleveland Clinic is a nonprofit multispecialty academic medical center that integrates clinical and hospital care with research and education. Located in Cleveland, Ohio, it was founded in 1921 by four renowned physicians with a vision of providing outstanding patient care based upon the principles of cooperation, compassion and innovation. Cleveland Clinic has pioneered many medical breakthroughs, including coronary artery bypass surgery and the first face transplant in the United States. Cleveland Clinic is consistently recognized in the U.S. and throughout the world for its expertise and care. Among Cleveland Clinic’s 81,000 employees worldwide are more than 5,743 salaried physicians and researchers, and 20,160 registered nurses and advanced practice providers, representing 140 medical specialties and subspecialties. Cleveland Clinic is a 6,690-bed health system that includes a 173-acre main campus near downtown Cleveland, 23 hospitals, 276 outpatient facilities, including locations in northeast Ohio; Florida; Las Vegas, Nevada; Toronto, Canada; Abu Dhabi, UAE; and London, England. In 2023, there were 13.7 million outpatient encounters, 323,000 hospital admissions and observations, and 301,000 surgeries and procedures throughout Cleveland Clinic’s health system. Patients came for treatment from every state and 132 countries. Visit us at Follow us at News and resources available at

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