Cleveland Clinic Children’s 2022-2023 U.S. News Rankings: Innovations, Patient Stories and Highlights

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For the 14th consecutive year, Cleveland Clinic Children’s is ranked among the nation’s top 50 pediatric hospitals.

Cleveland Clinic Children’s – an integral part of Cleveland Clinic, which was ranked as the nation’s No.2 hospital in 2021 by U.S. News – earned national recognition in nine specialties.

Cleveland Clinic has cared for infants, children, and adolescents since its doors first opened in 1921. That history of pediatric caregiving has blossomed into Cleveland Clinic Children’s, standing today as one of America’s leading and largest providers of comprehensive pediatric care. Now, it’s more than 300 pediatricians, practitioners and specialists – and more than 50 outpatient sites – provide the full spectrum of primary, specialty, and sub-specialty care to the largest patient population of any children’s hospital in Northeast Ohio.

Inspiring Patient Stories

Surgery on Baby in Womb Removes Life-Threatening Tumor on Heart
When Rylan was a 25-week-old fetus, doctors discovered a massive tumor on his heart. Without surgery in the womb to remove it, he would not survive. A multidisciplinary team of Cleveland Clinic and Cleveland Clinic Children’s doctors and nurses performed the rare and complex lifesaving fetal surgery by intricately removing the tumor.

Courtesy: Cleveland Clinic

Hendrix the Brave Battles Mightily Against Hunter Syndrome
If you met Hendrix, you’d find yourself under the spell of a superhero boy whose family and friends call “Hendrix the Brave.” He’s trying mightily to live with and overcome the effects of a rare disease called Hunter syndrome. Once a month, Hendrix receives a form of enzyme replacement therapy — an infusion of a drug directly into his spinal fluid through a special port in his back. 

Courtesy: Cleveland Clinic

Boy Needs Heart Transplant After Learning Shocking Diagnosis
Evan’s health declined rapidly and without much warning. He had end-stage heart failure, likely caused by a genetic condition called left ventricular noncompaction cardiomyopathy. When medications weren’t improving his health, doctors knew he would need a heart transplant to survive. 

Courtesy: Felisha Culp (left) and Cleveland Clinic (right)

Teen Baseball Player Back on Field After Rare Stroke
One minute Robbie is training for baseball, the next he’s in the ICU suffering from a rare type of stroke. More than a year later, he’s been able to finish school on time and get back to playing ball.

Courtesy: Christine Boyce

Research & Highlights

Healthy Diets Reduce Cardiovascular Risk Factors in Children Who Are Overweight
A Cleveland Clinic-led research team found statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced a variety of cardiovascular disease risks. The study, which published in the Journal of Clinical Pediatricspaired parents and children together throughout trial.

Cleveland Clinic Trial to Test Gene Therapy as Treatment of Sickle Cell
Cleveland Clinic researchers are enrolling patients in a clinical trial that aims to work toward a cure for sickle cell disease, by changing the patient’s genetics. Sickle cell disease, a genetic blood disorder, is a painful and debilitating condition for which there are few approved therapies.

Study Reveals Burden of Pediatric Heart Failure in the United States
Findings from a new Cleveland Clinic Children’s study found a rise in pediatric heart failure-related emergency department visits and primary heart failure hospitalizations between 2012 and 2016. Congenital heart disease, cardiomyopathy and arrhythmias were responsible for the majority. While there have been numerous adult studies highlighting the incidence of heart failure, this study, which was published in the Journal of the American College of Cardiology, is the first to look into the national burden of pediatric heart failure across all pediatric age groups in the U.S. healthcare system regardless of insurance status.

Lead Safety Becomes Cleveland Clinic’s Top Priority for Community Health
Lead poisoning affects more than 1,000 children every year in the city of Cleveland, more than four times the national average. In early 2022, Cleveland Clinic pledged $50 million to the Lead Safe Cleveland Coalition and the United Way of Greater Cleveland. The funds will be used to identify and remove harmful sources of lead exposure from Cleveland homes.