Locations:
Search IconSearch
April 23, 2024/Daily Health Stories

Safely Switching Allergy Medications

An allergist explains why some individuals may experience itching after they stop taking certain allergy medications.

Media Contact

Cleveland Clinic News Service | 216.444.0141

We’re available to shoot custom interviews & b-roll for media outlets upon request.

Media Downloads

CCNS health and medical content is consumer-friendly, professional broadcast quality (available in HD), and available to media outlets each day.

CLICK HERE to download soundbites, b-roll, script and web article.

For download password, contact ccnewsservice@ccf.org

CLEVELAND - If you’ve ever noticed itchiness after stopping an allergy medication, you might be surprised to hear that it could be a withdrawal symptom.

Sandra Hong, MD, allergist for Cleveland Clinic, said it’s not very common, but it can happen with certain antihistamines.

“There are certain individuals that will actually notice with the long-acting non-sedating antihistamines --the ones that can cause a little bit of sleepiness, those can actually cause people to have a severe itch when they've been using it daily for a long period of time, and then they just stop it immediately,” Dr. Hong explained.

Dr. Hong said to help avoid itchiness, consider switching to another over-the-counter allergy medication that is “non-sedating.”

You could also wean off the original allergy medication slowly.

So instead of taking it daily, switch to every other day.

Another option is to take children’s allergy medication and reduce your dosage amount that way.

Dr. Hong said part of why certain antihistamines can cause itchiness after you stop taking them is because of the ingredients, and how they cross the blood-brain barrier.

However, it’s important to note that doesn’t mean they’re any less safe.

“I've had some patients actually think that it was their severe allergies that were affecting them. And so, they felt like I have to be back on it again, and I need to continue taking it and taking it,” she said. “Typically, if your allergies started off with kind of more upper airway, so itchy eyes, itchy nose, itchy ears, we wouldn't expect you to all of a sudden get head to toe with itchiness.”

If you have any concerns about your allergy medication or possible withdrawal symptoms, it’s best to consult with an allergist.

About Cleveland Clinic

Cleveland Clinic is a nonprofit multispecialty academic medical center that integrates clinical and hospital care with research and education. Founded in 1921 by four renowned physicians with a vision of providing outstanding patient care based upon the principles of cooperation, compassion and innovation, Cleveland Clinic has pioneered many medical breakthroughs, including coronary artery bypass surgery and the first face transplant in the United States. Cleveland Clinic is consistently recognized in the U.S. and throughout the world for its expertise and care. Among Cleveland Clinic’s 83,000 employees worldwide are more than 6,600 salaried physicians and researchers, and 21,900 registered nurses and advanced practice providers, representing 140 medical specialties and subspecialties. Cleveland Clinic is a 6,725-bed health system that includes a 173-acre main campus near downtown Cleveland, 23 hospitals, 300 outpatient facilities, including locations in northeast Ohio; Florida; Las Vegas, Nevada; Toronto, Canada; Abu Dhabi, UAE; and London, England. In 2025, there were 15.9 million outpatient encounters, 343,000 hospital admissions and observations, and 336,000 surgeries and procedures throughout Cleveland Clinic’s health system. Visit us at clevelandclinic.org. Follow us at x.com/CleClinicNews. News and resources are available at newsroom.clevelandclinic.org.

Editor’s Note: Cleveland Clinic News Service is available to provide broadcast-quality interviews and B-roll upon request.

Latest Daily Health Stories

Dark chocolate

Why Dark Chocolate Can Be A Sweet Treat for Easter

Dani Reyes

Giving Hope: Young Girl with Autism Finds Voice Thanks to Therapy

Person laughing

Why a Dose of Laughter is Good for You

Cottage cheese

What Is the Craze with Cottage Cheese?

Child playing soccer

Teaching Kids about Sportsmanship

New clothes

Should You Wash New Clothes Before Wearing Them?

Wooded area

Preventing Tick Bites This Spring

Person sitting on bench

When Feeling Tired Could Be Something More