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March 20, 2025/Innovations

Health Tech 2025: A View from Cleveland Clinic Ventures

As healthcare marches into 2025, the industry stands on the brink of pivotal changes. Venture funding for digital health is regaining momentum, particularly for solutions that modernize infrastructure, enhance care delivery, and empower patients. Todd Schwarzinger, MBA, Partner, Cleveland Clinic Innovations Ventures, shares insights on how new partnerships and technologies are reshaping the future of care.

An image of Cleveland Clinic Caregivers hosting a meeting.

Funding Landscape & Consolidation

After a period of recalibration, investment in health tech is trending upward again. Early-stage deals are robust, focusing on artificial intelligence (AI)-driven workflows, advanced data platforms, and tools that close gaps in care. Consolidation is also set to intensify, as larger incumbents seek niche innovators to accelerate their strategic aims. For startups, this environment offers a path to meaningful exits, yet it underscores the need for strong market validation, defensible technology, and clinical traction from day one.

The Rise of AI in Care

AI has outgrown its role as a mere administrative assistant and is poised to become a core facilitator of clinical outcomes. Organizations are piloting AI in areas like radiological analysis, patient risk stratification, and ambient clinical documentation. For instance, Cleveland Clinic’s adoption of Ambience illustrates how AI-driven, ambient scribe technology can transform administrative burdens into seamless experiences. By automatically capturing and synthesizing interactions during patient visits, providers can focus on delivering empathic, high-quality care rather than wrestling with cumbersome data entry.

Despite AI’s promise, challenges remain. Trust, regulation, and operational integration are top of mind for clinicians who rely on accurate, bias-free outputs. New guidelines on algorithmic transparency and data privacy will shape how quickly, and safely, these innovations scale throughout the industry.

Modernizing Healthcare Infrastructure

Outdated systems and fractured data flows have long hampered healthcare’s ability to innovate. But new mandates, payer incentives, and shifting consumer expectations are spurring renewed investment in foundational upgrades. Cloud-based platforms, standardized APIs, and compliance-ready data services are all fueling more unified patient records and real-time analytics.

Cleveland Clinic’s partnership with Dyania Health exemplifies how modern infrastructure can streamline the patient journey. By automating the reading of entire EMR's with their Synapsis AI system, Dyania can flag patients' complex and dynamic characteristics at the exact moment when they could benefit from participation in a clinical trial, accelerating research and improving patient access to cutting-edge treatments. Solutions like these, built for interoperability and seamless workflows paired with high accuracy and performance, are becoming cornerstones of a high-functioning, future-proof healthcare system.

Consumer-Centric Trends

Patients increasingly expect healthcare experiences that are transparent, convenient, and responsive. Telehealth, online scheduling, and digital coaching tools are now considered table stakes rather than nice-to-haves. Cleveland Clinic’s use of Ayble Health, an application that supports patients with inflammatory bowel disease (IBD) through tailored care plans, is a prime example of how digital platforms can expand engagement and long-term management. As employers and insurers deepen their commitment to proactive health strategies, digitally savvy startups offering direct consumer benefits stand to thrive.

What’s Next?

Amid shifting payment models, startups must align their value propositions with measurable outcomes, robust data security, and clear regulatory paths. Investors increasingly favor companies that solve genuine clinical problems and demonstrate sustained impact. At Cleveland Clinic Ventures, we invite innovators to collaborate with us, leveraging real-world experience, strategic partnerships, and a patient-centric ethos to drive meaningful change.

By staying attuned to evolving incentives, embracing purposeful collaborations, and maintaining a laser focus on clinical and operational value, forward-thinking teams can build the foundation for a more effective, equitable, and dynamic healthcare ecosystem in 2025 and beyond.

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